Sofia Costa

  • Cambridge, United Kingdom, GB

Work History

Work History
Apr 2014 - Present

Research Assistant

Hutchison/MRC Research Centre
Oct 2013 - Mar 2014

Albert Renolds Travel Fellowship for Young Scientists

University of Barcelona
Sep 2012 - Sep 2013

MSc. Student

Faculdade de Ciências da Universidade de Lisboa
Oct 2009 - Sep 2013

PhD student

Faculdade de Medicina Veterinária

Education

Education
Jan 2015 - Jan 2015

Escola Secundária do Cartaxo
Jan 2003 - Jan 2006

MSc

Faculdade de Medicina Veterinária
Jan 1997 - Jan 2003

BSc

Universidade de Trás-os-Montes e Alto Douro

Text Section

Research papers

  • Edward T Chouchani, Victoria R Pell, Edoardo Gaude, Dunja Aksentijevic, Stephanie Y Sundier, Ellen L Robb, Angela Logan, Sergiy M Nadtochiy, Emily N J Ord, Anthony C Smith, Filmon Eyassu, Rachel Shirley, Chou-hui Hu, Anna J Dare, Andrew M James, Sebastian Rogatti, Richard C Hartley, Simon Eaton, Ana S H Costa, Paul S Brookes, Sean M Davidson, Michael R Duchen, Kourosh Saeb-parsy, Michael J Shattock, Alan J Robinson, Lorraine M Work, Christian Frezza, Thomas Krieg, Michael P Murphy (2014). Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature 515,   431–435.
  • Paula Mera, Joan Francesc Mir, Gemma Fabriàs, Josefina Casas, Ana S.H. Costa, Maria Ida Malandrino, José-Antonio Fernández-López, Xavier Remesar, Su Gao, Shigeru Chohnan, Maria Sol Rodríguez-Peña, Harald Petry, Guillermina Asins, Fausto G. Hegardt, Laura Herrero, Dolors Serra (2014). Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile. Plos One. 12; 9(5):e97195.
  • A.S.H. Costa, R.J.B. Bessa, V.M.R. Pires, R.M.A. Pinto, C.M.G.A. Fontes, J.A.M. Prates (2014). Is hepatic lipid metabolism of beef cattle influenced by breed and dietary silage level? BMC Veterinary Research, 10: 65.
  • P.A. Lopes, A.S.H. Costa, P. Costa, V.M.R. Pires, M.S. Madeira, F. Achega, R.M.A. Pinto, J.A.M. Prates (2014). Contrasting cellularity on fat deposition in the subcutaneous adipose tissue and longissimus lumborum muscle from lean and fatty pigs under dietary protein reduction. Animal, 8: 629-637.
  • Ana S.H. Costa, Virgínia M.R. Pires, Carlos M.G.A. Fontes, José A.M. Prates (2013). Expression of genes controlling fat deposition in two genetically diverse beef cattle breeds, Alentejana and Barrosã, fed high or low silage diets. BMC Veterinary Research, 9, 118.
  • Ana S.H. Costa, Marta P. Silva, Cristina P.M. Alfaia, Virgínia M.R. Pires, Carlos M.G.A. Fontes, Rui J.B. Bessa, José A.M. Prates (2013). Genetic background and diet impact beef fatty acid composition and stearoyl-CoA desaturase mRNA expression. Lipids, 48: 369-381.
  • Ana S.H. Costa, Paulo Costa, Rui J.B.Bessa, José P.C. Lemos, Jorge A. Simões, José Santos-Silva, Carlos M.G.A. Fontes, José A.M. Prates (2013). Carcass fat partitioning and meat quality of Alentejana and Barrosã young bulls fed high or low maize silage diets. Meat Science, 93: 405-412.
  • Marta S. Madeira1, Virgínia R. Pires1, Cristina M. Alfaia, Ana S.H. Costa, Richard Luxton, Olena Doran, Rui J. B. Bessa, José A.M. Prates (2013). Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White × Landrace × Pietrain crossbred pigs. British Journal of Nutrition, 110: 216-229. (1 = authors who contributed equally)
  • José M. Pestana, Ana S. H. Costa, Cristina M. Alfaia, Paulo Costa, Susana V. Martins, Susana P. Alves, Rui J. B. Bessa, José A. M. Prates (2012). Lipid composition and nutritional quality of intramuscular fat in Charneca-PDO beef. European Food Research and Technology, 234:187–196.
  • José M. Pestana, Ana S. H. Costa, Susana P. Alves, Susana V. Martins, Cristina M. Alfaia, Rui J. B. Bessa, José A. M. Prates (2012). Seasonal changes and muscle type effect on the nutritional quality of intramuscular fat in Mirandesa-PDO veal. Meat Science 90: 819–827.
  • Ana S.H. Costa1, Paula A. Lopes1, Marta Estevão, Susana V. Martins, Susana P. Alves, Rui M. A. Pinto, Hugo Pissarra, Jorge J. Correia, Mário Pinho, Carlos M.G.A. Fontes, José A.M. Prates (2012). Contrasting cellularity and fatty acid composition in fat depots from Alentejana and Barrosã bovine breeds fed high and low forage diets. International Journal of Biological Sciences, 8: 214–227. (1 = authors who contributed equally)
  • P. Costa1, J.P.C. Lemos1, P.A. Lopes, C.M. Alfaia, A.S.H. Costa, R.J.B. Bessa, J.A.M. Prates (2012). Effect of low- and high-forage diets on meat quality and fatty acid composition of Alentejana and Barrosã beef breeds. Animal 6: 1187–1197. (1 = authors who contributed equally)
  • José M. Pestana, Ana S. H. Costa, Susana I. V. Martins, Cristina M. Alfaia, Susana P. Alves, Paula A. Lopes, Rui J. B. Bessa, José A. M. Prates (2012). Effect of salughter season and muscle type on the fatty acid composition, including conjugated linoleic acid isomers and nutritional value of intramuscular fat in organic beef. Journal of the Science of Food and Agriculture, 92: 2428–2435.
  • AP Martins1, PA Lopes1, ASH Costa, SV Martins, NC santos, JAM Prates, TF Moura, G Soveral (2011). Differential mesenteric fat deposition in bovines fed on silage or concentrate is independent of glycerol membrane permeability. Animal 5: 1949–1956. (1 = authors who contributed equally)
  • Graça Ferreira-Dias, Ana S. Costa, Luísa Mateus, Anna J. Korzekwa, António Galvão, Dale A. Redmer, Karolina Lukasik, Anna Z. Szóstek, Izabela Woclawek-Potocka, Dariusz J. Skarzynski (2011). Nitric oxide stimulates progesterone and prostaglandin E2 secretion as well as angiogenic activity in the equine corpus luteum. Domestic Animal Endocrinology, 40: 1–9.
  • Cristina MM Alfaia, Susana P Alves, Anabela F Lopes, Maria JE Fernandes, Ana SH Costa, Carlos MGA Fontes, Matilde LF Castro, Rui JB Bessa, José AM Prates (2010). Effect of cooking methods on fatty acids, conjugated isomers of linoleic acid and nutritional quality of beef intramuscular fat. Meat Science 84, 769–777.
  • José M. Pestana, Susana I.V. Martins, Cristina M.M. Alfaia, Paula A. Lopes, Ana S.H. Costa, Rui J.B. Bessa, Matilde L.F. Castro, José A.M. Prates (2009). Content and distribution of conjugated linoleic acid isomers in bovine milk, cheese and butter from Azores. Dairy Science and Technology, 89: 193–200.
  • Cristina P.M. Alfaia, Susana P. Alves, Susana I.V. Martins, Ana S.H. Costa, Carlos M.G.A. Fontes, José P.C. Lemos, Rui J.B. Bessa, José A.M. Prates (2009). Effect of the feeding system on intramuscular fatty acids and conjugated linoleic acid isomers of beef cattle, with emphasis on their nutritional value and discriminatory ability. Food Chemistry 114, 939–946.
  • Rosário P. Roberto da Costa, Ana S. Costa, Anna J. Korzekwa, Rafal Platek, Marta Siemieniuch, António Galvão, Dale A. Redmer, José Robalo Silva, Dariusz J. Skarzynski, Graça Ferreira-Dias (2008). Actions of a nitric oxide donor on prostaglandin production and angiogenic activity in the equine endometrium. Reproduction, Fertility and Development, 20: 1–10.
  • Ferreira-Dias G., Mateus L., Costa A.S., Solá S., Ramalho R.M., Castro R.E., Rodrigues C.M.P. (2007). Progesterone and caspase-3 activation in equine cyclic corpora lutea. Reproduction in Domestic Animals, 42: 380386.
  • Ferreira-Dias G., Costa A.S., Mateus L., Korzekwa A., Redmer D.A., Skarzynski D.J. (2006). Proliferative processes within the equine corpus luteum may depend on paracrine progesterone actions. Journal of Physiology and Pharmacology, 57, supp 8, 139–151.
  • Costa, A.S., Mateus, L., Redmer D., Skarzynski, D.J., Ferreira-Dias, G. (2006). Is progesterone a paracrine regulator of endothelial cell proliferation in equine corpora lutea? Reproduction in Domestic Animals, 41: 363.

 

Oral Communications

  • Costa, A.S.H., Bessa, R.J.B., Alfaia, C.P.M., Pires, V.M.R., Fontes, C.M.G.A., Prates, J.A.M. Effect of breed and diet on beef cattle fatty acid profile and SCD mRNA expression. 63rd Annual Meeting of the European Association for Animal Production - August 27th31st 2012, Bratislava, Slovakia
  • Costa, A.S.H., Costa, P., Bessa, R.J.B., Lemos, J.P.C., Simões, J.A., Santos-Silva, J., Fontes, C.M.G.A., Prates, J.A.M. Productive and carcass traits of Alentejana and Barrosã bulls fed high or low silage diets. 63rd Annual Meeting of the European Association for Animal Production - August 27th31st 2012, Bratislava, Slovakia
  • Lopes, P.A.; Costa, P.; Pires, V.; Madeira, M.S.; Achega, F.; Costa, A.S.H.; Prates, J.A.M. Assessing fat deposition between subcutaneous fat tissue and muscle in lean and obese pigs fed on reduced protein diets. 10th Euro Fed Lipid Congress, Cracow, Poland, 23th – 26th September 2012
  • Ana S. H. Costa, Paula A. Lopes, Marta Estevão, Susana V. Martins, Susana P. Alves, Rui M. A. Pinto, Hugo Pissarra, Jorge J. Correia, Mário Pinho, Carlos M.G.A. Fontes, José A.M. Prates. Differential cellularity and fatty acid profile in subcutaneous and mesenteric fat depots from Portuguese bovine breeds. 57th International Congress of Meat Science and Technology, Ghent, Belgium, 7th – 12th August 2011
  • R.P. Roberto da Costa, A.S. Costa, A. Korzewka, R. Platek, D.A. Redmer, D.J. Skarzynski, G. Ferreira-Dias, 2007. Effect of TNFa on prostaglandin F2a and E2 release and endothelial cell proliferation by equine endometria. 4th International Expert Workshop on Equine Reproductive Medicine - the barren mare, Leipzig, Germany, 22nd – 25th November 2007
  • G. Ferreira-Dias, A. S. Costa, L. Mateus, D.A. Redmer, D.J. Skarzynski. Proliferative processes within equine corpus luteum may depend on paracrine actions. XXI Congress of the Polish Physiological Society “Physiology without limits”, Department of Physiological Sciences, Warsaw Agricultural University, Warsaw, Poland  14th – 16 th September 2006

 

Poster Communications

 

  • Pestana, J.M., Costa, A.S.H., Martins, S.V., Alfaia, C.M., Alves, S.P., Lopes, P.A., Bessa, R.J.B., Prates, J.A.M. Lipid composition and nutritional quality of intramuscular fat in organic beef. XI Congresso de Nutrição e Alimentação, Oporto, Portugal, 24th – 25th May 2012.
  • Ana S.H. Costa, Paulo Costa, Cristina M. Alfaia, Paula A. Lopes, José Pedro C. Lemos, José A. M. Prates. Meat quality and sensory attributes of two Portuguese bovine breeds, Alentejana and Barrosã, under distinct feeding regimens. 57th International Congress of Meat Science and Technology, Ghent, Belgium, 7th – 12th August 2011.
  • Virgínia M.R. Pires, Ana S.H. Costa, Carlos M.G.A. Fontes, José A. M. Prates. Expression of SCD and LPL genes and fatty acid composition in subcutaneous adipose tissue of two portuguese cattle breeds. International Congress of Meat Science and Technology, Ghent, Belgium, 7th – 12th August 2011.
  • Paula A. Lopes, Ana P. Martins, Ana S.H. Costa, Susana V. Martins, Nuno C. Santos, José A. M. Prates, Teresa F. Moura, Graça Soveral. Contrasting mesenteric fat deposition in bovines fed on silage or concentrate is independent of membrane permeability to glycerol. . 9th Euro Fed Lipid Congress. Rotterdam, Netherlands, 18th – 21st September 2011.
  • José M. Pestana, Ana S.H. Costa, Eliana Jerónimo, Cristina M. M. Alfaia, Mafalda M. Nascimento, Paulo Costa, Paula A. Lopes, José A. M. Prates, José Santos-Silva, Rui J. B. Bessa. Effect of propylene glycol and linseed oil supplementation on intramuscular fatty acids of lamb meat. International Conference on Food Innovation, FoodInnova. Valencia, Spain, 25th – 29th October, 2010.
  • Marta S. Madeira, Cristina M. Alfaia, Ana S.H. Costa, Rui J. B. Bessa, José A. M. Prates. Contents of total cholesterol and lipid-soluble antioxidant vitamins in edible swine by-products. 8th Euro Fed Lipid Congress. Munich, Germany, 21st – 24th November 2010.
  • José M. Pestana, Susana I.V. Martins, Cristina M.M. Alfaia, Paula A. Lopes, Ana S.H. Costa, Matilde L.F. Castro, Rui J.B. Bessa, José A.M. Prates, 2009.Fatty acid composition and related nutritional indexes of commercial Azorean butters. 9th Meeting of Food Chemistry, Angra do Heroísmo, Terceira, Azores, 29th April – 2nd May 2009
  • A.S. Costa, L. Mateus, D.A. Redmer, D.J. Skarzynski, G. Ferreira-Dias, 2006. Effects of TNF and nitric oxide donor on equine luteal production of factor(s) that stimulate endothelial cell proliferation. 10th Jubilee Conference of European Society for Domestic Animal Reproduction, Portoroz-Lipica, Slovenia, 7th – 9 th September 2006
  • A.S. Costa, L. Mateus, D.A. Redmer, D.J. Skarzynski, G. Ferreira-Dias, 2006. Is progesterone a paracrine regulator of endothelial cell proliferation in equine corpora lutea? 10th Jubilee Conference of European Society for Domestic Animal

Portfolio

Skills

Skills

Genetics

Statistics

Bioinformatics

Primer Design

PCR

Immunohistochemistry

RIA

ELISA

Chromatography

Biochemistry

HPLC

RNA isolation

Research

SAS

Cell Culture

Molecular Biology

Food Chemistry