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Education

Projects and Research Experiences

Jul 2014Nov 2015

R&D Assistant

Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), India

Supervisor: Prof. Udaykumar Ranga, Molecular Biology and Genetics Unit

The project was to explore the scope of intradermal needle-free injection for mounting a strong and persistent antigen-specific immune response against DNA vaccine. We identified an impairment in humoral (antibody) response in needle- free immunization as compared to the conventional intramuscular immunization. We demonstrated the cause of the problem and provided an effective solution to it.

Dec 2013 May 2014

BTech. Final Year Thesis

NIT Durgapur, WB, India.

Supervisor: Dr. Dalia Dasgupta Mandal, Department of Biotechnology

The objective of the project was to study the genotoxic effect of simulated wastewater (SWW) containing organic pollutants on Allium cepa (onion plants) and to develop its possible bioremediation. I found that the organic pollutants in SWW are highly genotoxic and growth inhibiting to A. cepa. We isolated a bacteria that can effectively and drastically reduce the organic pollutants.

May 2013Jul 2013

Summer Intern

Biocomplexity Institute, Indiana University, Bloomington, IN, USA.

PI: Prof. James A. Glazier, Director of Biocomplexity Institute

My project was to identify the effects of arsenic exposure on regulation of angiogenesis by VEGF-A, a known inducer of angiogenesis, in zebrafish embryo using confocal microscopy. I found a negative correlation between dose of arsenic exposure and VEGF-A expression around intrasomital vessels in zebrafish embryos. 

Dec 2012Jan 2013

Winter Trainee

Chittaranjan National Cancer Institute, India.

Supervisor: Dr. Soumitra kumar Choudhuri, In-vitro Carcinogeneis and Cellular chemotherapy

The project was to observe the effects of Doxorubicin (drug) on cancer cells - in vitro and in vivo. As part of the training I learnt mouse handling and mammalian cell culture. 

May 2012Jul 2012

Volunteer 

National Institute of Biomedical Genomics, Kalyani, India.

Supervisor: Dr. S. K. Mohapatra

I worked on the project titled "Studying the Expressions of Selected Genes in Different Stages of Sepsis". In this project I compared gene expression at different stages of sepsis with that during health. It required a strong background in C programming and knowledge of Microsoft Excel along with basic understanding of immunology and molecular biology.

Publications

Arunachalam, P. S., Mishra, R., Selvam D.,Payeli, S. K., Stout, R.R., & Ranga, U. Toll-like receptor 9 activation rescues impaired antibody response in needle-free intradermal DNA vaccination. Nature Scientific Reports, in press.

Clendenon, S. G., Shirinifard, A., Zahedian, M., Sankaran, D. G., Mishra, R., McCollum, C. W., ... & Glazier, J. A. (2013). Arsenic inhibition of angiogenesis in zebrafish is due to downregulation of VEGFA (165) and VEGFR2. Molecular Biology of the Cell (Vol. 24).

Posters and Presentations

Arunachalam, P. S., Mishra, R., Selvam D.,Payeli, S. K., Stout, R.R., & Ranga, U. (2016). Toll-like receptor 9 activation rescues impaired antibody response in needle-free intradermal DNA vaccination. Poster presented at the Conference on Retroviruses and Opportunistic Infections, 2016.

Mishra, R., Behera, M., & Mandal, D. D. The genotoxic effect of simulated wastewater on Allium cepa and it’s possible bioremediation.  Poster presented at National Conference on Environment: Pollution and Protection, 2014.

Mishra, R., Zahed, M., Clendenon, S. G., Glazier, J. A. Effects of Arsenic Exposure on Regulation of Angiogenesis by VEGF-A in Zebrafish. Poster presented at the Centre for Research and Learning Summer Research Program Poster Session and Recognition Event, IUPUI, Indianapolis, IN, USA, 2013.

Clendenon, S. G., Shirinifard, A., Zahedian, M., Sankaran, D. G., Mishra, R., McCollum, C. W., ... & Glazier, J. A. Arsenic inhibition of angiogenesis in zebrafish is due to downregulation of VEGFA (165) and VEGFR2. Poster presented at the Annual Meeting of the American Society for Cell Biology, 2013.

Mishra, R., & Mazumdar, S. Simultaneous Power Generation and Gas Purification using Electrostatic Precipitator. Oral presentation at All India Students’ Engineering Congress, 2011.

Awards and Honors

2014

Silver Medalist

Department of Biotechnology, NIT, Durgapur.

Graduated with first class (Distinction).

May 2013Jul 2013

Khorana Program for Scholars Fellowship

by Indo-US Science and Technology Forum, UWisc and Govt. of India

Fully sponsored summer internship at Indiana University.

2011

Special Award for project

at All India Students’ Engineering Congress
2010

Certificate of Merit in Computer Science 

by Central Board of Secondary Education, India

Received for being among the top 0.1% of successful candidates in AISSCE 2010 (XII standard) in
Computer Science.

2006

Gold- medal for Project Presentation

at the National level of 14th National Children’s Science Congress 

Skills ( with current levels of expertise) 

English                              

(spoken, written and reading)

Hindi

(spoken, written and reading)

Bengali

(spoken)

(reading)

Odia

   (spoken)

Teaching and Volunteering Experiences

Provide free private tuition to kids from low- income families    Mar 2016- Present

Conducted an Immunology Hands-on Workshop on ELISPOT Assay      Mar 2015

for Integrated-PhD. Students of MBGU, JNCASR, India.

Trained and Supervised two Summer Students                                 Summer 2015

HIV-AIDS lab, JNCASR, India.

Served as Medical Volunteer in Village Medical Camps                             2012, 2013

(organized by National Service Scheme, India.)

Volunteered to teach primary school kids.                                     Jan 2013-Mar 2014

(with the  Bihari More Education Project (BMEP) at NIT Durgapur.)

   

I hereby declare that the information given above is true and correct.


                                                                                                                       08 June 2016
Ria Mishra                                                                                                   Kolkata, India.