Molecular Biologist--Master of Science Degree in Molecular, Cellular, & Biochemical Pharmacology

Seek to advance drug discovery and the development of therapeutic agents at pharmaceutical and biotech companies, research institutions, and government agencies.


I’m currently seeking opportunities to apply my research knowledge and skills to advance your research program. Willing to travel and relocate, I often travel to the Washington,DC/Baltimore area. Contact Information: michaelwilhide@gmail.com Research Interests Understanding the molecular and genetic mechanisms of human diseases to advance drug discovery, development of therapeutic agents, and improve diagnosis and care for patients. My overall goal is to discover novel classes of biomarkers and therapeutic targets using in-vivo models and translate that knowledge into the clinical realm to advance therapies for patients. Research Background Nuclear Factor Kappa B (NF-kB) is a transcription factor associated with cell survival and cell death outcomes after various myocardial ischemic insults. There was limited knowledge of the mechanism behind the differential effects of NF-kB following ischemic insults that prevented the identification of novel therapeutic targets for myocardial infarction. Action: Designed, executed, and analyzed molecular biology and gene expression experiments to investigate the role of NF-kB. Results: Discovered novel sets of genes that are involved in NF-kB-dependent cardioprotection and cell death. Significance: Identified therapeutic targets more appropriate for clinical development for the treatment of myocardial ischemic heart disease. Major Achievements • Wrote and was awarded a prestigious NIH predoctoral F31 Fellowship ($153,629) • First author and contributing author to manuscripts published in peer-reviewed journals (Journal of Molecular and Cellular Cardiology, Molecular Pharmacology, and Cardiovascular Toxicology) • Presented research findings at laboratory meetings, local seminars, and posters at national research conferences (Experimental Biology 2008 & 2009, International Society for Heart Research North American Section 2008)

Work History

Work History
2011 - Present

Seek to advance drug discovery and the development of therapeutic agents

Pharmaceutical and biotech companies, research institutions, and government agencies

• Finalized research article that was published in Journal of Molecular and Cellular Cardiology (Identification of a NF-κB cardioprotective gene program: NF-κB regulation of Hsp70.1 contributes to cardioprotection after permanent coronary occlusion) • Involved in local job search groups, e.g., the Job Search Focus Group of Hyde Park (Cincinnati) and Job Search Learning Labs-Anderson Township (Cincinnati) • Attend career workshops, seminars, networking events, and career/job fairs • Actively involved with LinkedIn in posting interesting career and science articles/news, active in current discussions, and networking with other members

2011 - Present


The Bio-Pharm (LinkedIn Group)

• Created a marketing plan and enhanced "The Bio-Pharm" LinkedIn group profile and rules, which resulted in a four-fold increase in members in less than two weeks (from 43 to 170+), active discussions and job postings without SPAM This group is for professionals and anyone interested in Biotech, Pharma, Medical/Health Care, and Life Sciences. The mission of the group is to hold active and intelligent discussions centering on diagnostics, medical devices, innovations, clinical trials, research, policy, QA, and current science news. We recommend that our members be actively engaged in posting topics/articles and contributing to the discussions.

Aug 2011 - Sep 2011

Biochemist I (Bioanalytical/Bioprocess Scientist)

Merck (Contractor from New Age Clinical)

(Short-term assignment) • Assisted in analyzing target proteins using HPLC

Jul 2003 - Jul 2010

Research Assistant

University of Cincinnati College of Medicine

• Designed and optimized in vivo and in vitro experiments to investigate the role of Nuclear Factor Kappa-B (NF-kB) following myocardial ischemic insults • Executed molecular biology assays to confirm activation of NF-kB following ischemia and determined when NF-kB-dependent cardioprotection occurred • Performed, analyzed, and validated gene expression results that established novel genes involved in the NF-kB dependent cardioprotection and cell death outcomes • Researched and applied scientific literature to employ new knockout mouse models to examine the mechanism of particular genes (e.g. hspa1a and hspa1b) • Identified therapeutic targets more appropriate for clinical development for the treatment of ischemic heart disease • Organized and successfully presented research results in published manuscripts, posters at national research conferences, local seminars, and laboratory meetings • Assisted lab surgeons with in vivo myocardial ischemic models and collaborated with colleagues

May 2002 - Dec 2002

Research Assistant (Co-op Student)

Wood Hudson Cancer Research Laboratory

• Maintained and prepared various cancer cell cultures • Examined proliferation (PCNA Staining) and apoptotic cell death (TUNEL) on human tumor paraffin sections • Analyzed data and assisted in administrative tasks


Jul 2010

Master of Science

University of Cincinnati College of Medicine

Thesis: Hsp70.1 contributes to NF-κB paradox after myocardial ischemic insults National Research Service Award (NRSA) NIH Predoctoral F31 Fellowship (8/05-7/09: $153,629) University Graduate Assistantship, University of Cincinnati 2003-2005

Activities and Societies:

  • Co-mentored a biology undergraduate student 2008-2009
  • Seminar, University of Cincinnati Pharmacology & Pharmacy 2008 Student Research Retreat, HSP70 in Myocardial Ischemia: Isoform Specific Roles
  • Served as elected graduate student representative to Department of Pharmacology and Cell Biophysics Graduate Education Committee 2006-2007
  • Seminar, University of Cincinnati, ASPET Summer Undergraduate Fellowship Lecture Series 2006, Stem Cell Therapy: Good, Bad and the Ugly
Dec 2002

Bachelor of Science

College of Mount St. Joseph

Thesis: The effects of Herbicide RoundUp on the Early Development of the African Clawed Frog, Xenopus Laevis College of Mount St. Joseph Dean's List 2002 College of Mount St. Joseph Sisters of Charity Scholarship 1998-2002

Activities and Societies:

  • Member and Secretary, Xi Gamma Chapter of Beta Beta Beta Biological Honor Society 2001-2002