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Work experience

Dec 2013Nov 2015

Research Associate

Karolinska Institutet, Stockholm, Sweden
  • Study of cytotoxicity, genotoxicity and inflammatory effects of organic and inorganic gold-standard nanoparticles using in vitro and ex vivo human cell-culture models.
  • Scientific reporting of findings to European Union Commission, under EU FP7-NanoReg program.
  • ADME study of polymer functionalized and non-functionalized carbon-based nanotubes within normal and diseased animal models with focus on future nanomedicine applications.
  • Teaching nanotoxicology and high-throughput screening in Masters in toxicology program, Karolinska Institutet, Stockholm.
  • Assistant in organizing 'Graduate course in nanotoxicology 2015' at international level and teaching.
  • Co-supervision of Masters and Doctoral program students in their research and thesis works.
Jun 2012Nov 2013

Senior Postdoctoral Researcher

Karolinska Institutet, Stockholm, Sweden
  • Study of enzymatic biodegradation of carbon-based nanomaterials by human origin immune cells under in vitro and ex vivo condition with focus on future nanomedicine applications.
  • Teaching nanotoxicology and high-throughput screening in Masters in toxicology program, Karolinska Institutet, Stockholm, Sweden.
  • Co-supervision of Masters and Doctoral program students in their research and thesis works.
May 2008Oct 2011

Postdoctoral researcher

Dublin Institute of Technology, Dublin, Republic of Ireland.
  • Study of cytotoxicity, genotoxicity and oxidative stress inducing effects silica-based Zeolite nanoparticles with commercial applications in humans during respiratory and dermal exposures using in vitro human origin cell-culture models.
  • Development of in vitro 3-D biological matrices for rapid Raman spectroscopy screening of mammalian cells.
  • Established high-throughput microcomet assay.
  • Co-supervision of Masters and Doctoral program students in their research and thesis works.
Feb 2005Jul 2005

Guest Scientist

University Hospital Essen, Essen, Germany
  • Determination of cytotoxicity, genotoxicity and oxidative stress inducing capacity of asbestos fibers and fine dust particles in human respiratory system using in vitro mammalian cell culture models.
  • Established high-throughput microcomet assay.
May 2002Oct 2004

Project Assistant

Indian Institute of Toxicological Research, Lucknow, India
  • Study of asbestos fibers induced cytotoxicity and genotoxicity in ex vivo cultures of human whole blood.
  • Collection of biological samples (nasal lavage and peripheral blood) from controls and asbestos factory workers and screening for inflammation and genotoxicity.

Education

Sep 2005Oct 2008

Ph.D. in Toxicology

University of Duisburg-Essen, Essen, Germany

Thesis title: Comparative analysis of fine and nanoparticles for cellular uptake, oxidative stress and genomic damage in human lung cells. Grade: Magna cum laude

19982000

M.Sc in Life Sciences

University of Lucknow, Lucknow, India
19951998

B.Sc in Life Sciences

University of Lucknow, Lucknow, India

Skills

In-vitro cell culture
High-throughput screening
  • Flow-cytometry
  • Luminexanalysis.
  • Microcomet assay .
Molecular biology
  • RT-PCR.
  • Western blotting.
  • SiRNA based analysis.
  • ELISA
Genotoxicity analysis
  • Microcomet assay .
  • OECD 487.
  • OECD 473.
  • OECD 479.
Microscopy
  • Confocal microscopy.
  • Scanning electron microscopy.
Spectroscopy analysis
  • UV-Vis-NIR spectroscopy.
  • Raman spectroscopy.
  • MALDI-tof mass spectroscopy.
Nanometrology
  • Dynamic light scattering-based dynamic particle size distribution and zeta potential analysis.
  • Bruner-Emmett-Teller analysis.
  • Scanning electron microscope and EDX .
Computer-based applications
  • Electronic Lab Notebook (ELN)
  • Graphpad Prism.
  • MS-Office.
  • HTML5.
  • Photoshop.

Memberships

  • Member of United Kingdom registers for Toxicologists.
  • European Registered Toxicologist (ERT).

Awards

  • Research grant from Karolinska Institutet Foundation, 2015.
  • Research grant from Karolinska Institutet Foundation, 2014.
  • Research grant from Karolinska Institutet Foundation, 2013.
  • Best Poster Award, 2nd QNano conference, Czech Republic, 2013.
  • Travel grant from Health Research Board, Ireland for attending 'Molecular mechanism of cancer course' held at National Cancer Institute, Bethesda, United States, 2011.
  • Research grant (UREKA ) from Science Foundation of Ireland, Ireland, 2009.
  • Young Scientist Award for doctoral thesis from University of Duisburg-Essen, Germany, 2009.
  • Travel grant from Deutsche Forschungsgemeinschaft, Germany for attending 47th Society of Toxicology meeting, Seattle, United States, 2008.
  • Best poster award, EnTox conference, Dortmund, Germany, 2007.

List of Publications

https://scholar.google.se/citations?hl=en&user=Nc2j59UAAAAJ

References

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