Publications

10. J.Tang; A.M. Jofre; R.B. Kishore; J.E. Reiner; M.E. Greene; G.M. Lowman; J.S. Denker; C.

Willis; K. Helmerson; L. S. Goldner, Generation and Mixing of Subfemtoliter Volume

Aqueous Droplets On Demand.Analytical Chemistry, 81, 19, 8041 (2009).

9.J. Bowers; J. Mitchell; E. Beer; P.R. Buzby; M. Causey; J.W. Efcavitch; E. Giladi; M. Jarosz; E.

Krzymanska-Olejnik; L. Kung; D. Lipson; G.M. Lowman; S. Marappan; P. McInerney; A. Platt;

A. Roy; S.M. Siddiqi; K. Steinmann; J.F. Thompson, Novel Nucleotides as Virtual Terminators

for Next Generation DNA Sequencing of Mammalian DNA.Nature Methods, 6, 8, 593

(2009).

8.J.Tang; A.M. Jofre; G.M. Lowman; R.B. Kishore; J.E. Reiner; K. Helmerson; L. S. Goldner;

M.E. Greene, Green Fluorescent Protein in Inertially Injected Aqueous Nanodroplets.

Langmuir, 24, 9, 4975 (2008).

7.G.M. Lowman; P.T. Hammond, Solid-State Dye-Sensitized Solar Cell Incorporating a Porous

TiO2 Layer and a Layer-by-Layer Composite Electrolyte.Small, 1, 11, 1070 (2005).

6.G.M. Lowman; H. Tokuhisa; J.L. Lutkenhaus; P.T. Hammond, A Novel Solid-State

Polymer Electrolyte Consisting of a Porous Layer-by-Layer Polyelectrolyte Thin Film

and Oligoethylene Glycol. Langmuir, 20, 22, 9791 (2004).

5.G.M. Lowman; S.L. Nelson; S.M. Graves; G.F. Strouse; S.K. Buratto, Polyelectrolyte

– Quantum Dot Multilayer Films Fabricated by Combined Layer-by-Layer Assembly

and Langmuir – Schaefer Deposition. Langmuir, 20,6, 2057 (2004).

4.D. S. Sirbuly; G. M. Lowman; B. Scott; G. D. Stucky; S. K. Buratto, Patterned

     Microstructures of Porous Silicon by Dry Removal Soft Lithography.Advanced

Materials, 15, 2, 149 (2003).

3.G. M. Lowman; S. K. Buratto, Nanoscale Morphology of Polyelectrolyte Self-

Assembled Films Probed by Scanning Force and Near-Field Scanning Optical

Microscopy.Thin Solid Films, 405,135 (2002).

2.G. M. Lowman; N. Daoud; R. M. Case; P. J. Carson; S. K. Buratto, Local Energy

     Transfer in Self-Assembled Polyelectrolyte Films Probed by Near-Field Optics.

     Nano Letters, 1,12, 677 (2001).

1.G. M. Credo; G. M. Lowman; J.A. DeAro; P. J. Carson; D. L. Winn; S.K.

Buratto, Probing Nanoscale Photo-Oxidation in Organic Films Using Spatial

Hole Burning Near-Field Scanning Optical Microscopy. Journal of Chemical Physics, 112,

18, 7864 (2000). 

Proceedings Publications

3.A.M. Jofre, J. Tang, M.E. Greene, G.M. Lowman, N. Hodas, R.B. Kishore, K. Helmerson, L.S.

Goldner, Hydrosomes:Femtoliter Containers for Fluorescence Spectroscopy Studies.

Proceedings of the SPIE, 6644, 66440E (2007).

2.G.M. Lowman; H. Tokuhisa; J.L. Lutkenhaus; P.T. Hammond, Dye Sensitized Solar Cells

Incorporating Polyelectrolyte Multilayer Composites.Proceedings of the Materials

Research Society, 836, L1.5.1 (2004).

1.G.M. Lowman; S.K. Buratto, Nanoscale Morphology of Polyelectrolyte Self-Assembled Films

Probed by Scanning Force and Near-Field Scanning Optical Microscopy.Proceedings of

The American Chemical Society Division of Polymeric Materials: Science &

Engineering, 82, 249 (2001).

Honors and Awards

-National Research Council Postdoctoral Fellow (2005 – 2007)

-Presidential Scholarship, University of Oregon (1994 1998)

-Inorganic Chemistry Award, Dept. of Chemistry, University of Oregon (1998)

-American Chemical Society Certified Degree, University of Oregon (1998)

Presentations

13. G.M. Lowman; “Single Molecule DNA Sequencing” Presented at the Biochemistry and

Biophysics Seminar Series, Brandeis University, March 27, 2009. Waltham, MA. (Invited)

12. G.M. Lowman; H. Tokuhisa; J.L. Lutkenhaus; P.T. Hammond, “Solid-State Dye Sensitized

Solar Cells Incorporating Polyelectrolyte Multilayer Composites.”Presented at the 2004 fall

meeting of the Materials Research Society, Boston, MA.

11. G.M. Lowman; H. Tokuhisa; P.T. Hammond, “Design and Performance of Solid-State

Dye Sensitized Solar Cells Incorporating Polyelectrolyte Multilayer Composites.”

Presented at the 2003 spring meeting of the American Chemical Society, Anaheim,

CA.

10. G.M. Lowman; M. Berrettini; G. Khitrov; A. Javier; G.F. Strouse; S.K. Buratto,

“Multilayer Structures of Polyelectrolytes and Nanoparticles based on Layer-by-Layer

Assembly and Langmuir Blodgett Deposition.”Presented at the 2003 spring meeting of the

American Chemical Society, New Orleans, LA.

9.G.M. Lowman; M. Berrettini; G. Khitrov; A. Javier; G.F. Strouse; S.K. Buratto,

      “Multilayer Structures of Polyelectrolytes and Nanoparticles based on Layer-by-Layer Assembly and      

      Langmuir Blodgett Deposition.”Presented at the 2002 fall meeting of the American Chemical Society,      

      Boston, MA.

8.G.M. Lowman; N. Daoud; R.M. Case; P.J. Carson; S.K. Buratto, “Probing Local Energy

Transfer in Self-Assembled Polyelectrolyte Films Using Near-Field Optics.”Presented at the

2002 spring meeting of the American Chemical Society, Orlando, FL.

7.G.M. Lowman; N. Daoud; R.M. Case; P.J. Carson; S.K. Buratto, “Probing Local Energy

Transfer in Self-Assembled Polyelectrolyte Films Using Near-Field Optics.”Presented at the

2002 meeting of the Materials Research Society, San Francisco, CA.

6.G.M. Lowman; N. Daoud; R.M. Case; P.J. Carson; S.K. Buratto, “Probing Local Energy

Transfer in Self-Assembled Polyelectrolyte Films Using Near-Field Optics.”Presented at the

2002 spring meeting of the American Physical Society, Indianapolis, IN.

5.G.M. Lowman; N. Daoud; R.M. Case; P.J. Carson; S.K. Buratto, “Probing Local Energy

Transfer in Self-Assembled Polyelectrolyte Films Using Near-Field Optics.”Presented at the

2001 meeting of the Western Regional American Chemical Society, Santa Barbara, CA.

4.G.M. Lowman; S.K. Buratto, “Nanoscale Morphology of Polyelectrolyte Self-Assembled Films

Probed by Scanning Force and Near-Field Scanning Optical Microscopy.” Presented at Spring

2001 meeting of the American Physical Society, Seattle, WA.

3.G.M. Lowman; S.K. Buratto, “Nanoscale Morphology of Polyelectrolyte Self-Assembled Films

Probed by Scanning Force and Near-Field Scanning Optical Microscopy.” Presented at Spring

2001 meeting of the American Chemical Society, San Diego, CA.

2.G.M. Lowman; P.J. Carson; S.K. Buratto, “Probing Nanoscale Structure and Excited-State

Diffusion in Dye-labeled Polyelectrolyte Multilayers using NSOM.”Presented at Spring 2000

meeting of the American Chemical Society, San Francisco, CA.

1.G.M. Lowman; P.J. Carson; S.K. Buratto, “Probing Nanoscale Structure and Excited-State

Diffusion in Dye-labeled Polyelectrolyte Multilayers using NSOM.”Presented at Spring 2000

meeting of the Materials Research Society, San Francisco, CA.

Memberships

-American Chemical Society (1999-present)

-Materials Research Society (1998-2007)

-American Physical Society (2001-2008)

-Biophysical Society (2005-2008)

Research Experience

July 2010 - present

Staff Scientist, Life Technologies/Ion Torrent, Carlsbad, CA 92008

Enzyme Evolution Development Group – Ion Torrent (Feb. 2011-present)

-      Semiconductor-based DNA sequencing technology development

-      Hardware and chemical optimization for enzyme evolution mutant polymerases to

       enable longer, more accurate sequence data

-      Sample prep and chip loading innovation

Single Molecule DNA Sequencing (Jul. 2010 – Feb. 2011)

-Real-time single molecule DNA sequencing experiments by FRET

-Fundamental optical experiments (single-molecule, fluorescence correlation spectroscopy) probing the        

        mechanisms of phototoxicity in real-time single molecule DNA sequencing

March 2007 – May 2010

Scientist, Sequencing Development, Helicos Biosciences Corporation, Cambridge, MA 02139

Single Molecule DNA Sequencing

-Hardware and chemical development and optimization of single molecule DNA sequencing experiments

-Genomic-scale data analysis

-In-house and customer-related mechanical and reagent troubleshooting experiments

-Project Leader - High-Density DNA surface chemistry development

June 2005 – March 2007

National Research Council Postdoctoral Fellow, National Institute of Standards and Technology (NIST), Physics Laboratory, Gaithersburg, MD 20899-8443

Dr. Lori S. Goldner – Single Molecule Detection in Biological Systems

-Development of Confocal / Optical trapping microscope instrumentation

-Single Molecule Fluorescence Resonance Energy Transfer (FRET) experiments in solution and on surfaces

-Ultra-fast solution dynamics measurements – Time-Correlated Single Photon Counting (TCSPC)

June 2003 – June 2005

Postdoctoral Research Assistant, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139  

Prof. Paula T. Hammond – Fabrication of Solid-State Dye-Sensitized Solar Cells 

-Fabrication of TiO2 network films by various methods:  Sol-gel synthesis,

         layer-by-layer deposition, and screen-printing

-        Patterning of TiO2 network films by microcontact printing (mCP)

-Assembly and characterization (SEM & AFM) of ion conductive polyelectrolyte films for use as solid-state

          electrolytes in solid-state dye-sensitized solar cells

November 1998 – May 2003

Graduate Research Assistant, Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106

Prof. Steven K. Buratto – High Resolution Optical Microscopy of Self-Assembled Polyelectrolyte Thin Films

-      Conducted novel high-resolution optical microscopy (NSOM), AFM, and confocal microscopy / 

       spectroscopy experiments on thin films of polyelectrolytes, nanoparticle – polyelectrolyte hybrid films, and

       single molecule samples

-      Constructed custom NSOM / confocal microscope and sample scanning stage 

-      Conducted fundamental studies of LbL films using small angle X-ray diffraction and     

       Secondary Ion Mass Spectrometry (SIMS)

June 1997 – August 1998

Undergraduate Research Assistant, Department of Chemistry, University of Oregon, Eugene, OR 97403

Prof. Catherine J. Page - Layer-by-Layer Synthesis of Inorganic-Organic Multilayer Thin Films

Objective

Experienced research and development scientist with an emphasis on instrumentation and techniques to further innovation in the most important and fast-paced area in science today:  genomics and personalized medicine. 

Education

Education
Sep 1994 - Jun 1998

B.A.

University of Oregon

Also attended the Robert D. Clark Honors College at the University of Oregon.

Skills

Skills

Specialties

Single Molecule Microscopy and Spectroscopy Instrument Development and Design Optics Fluorescence Techniques Photophysics Near-Field Microscopy (NSOM) AFM XPS XRD SEM DNA Sequencing Dye and Nanoparticle characterization

References

References

Daniel Mazur

Timothy Harris

Tommie Lincecum

J. William Efcavitch

Paula Hammond

Lori Golder

Jayson Bowers

Mirna Jarosz

Steven Buratto