Director of Evidence Solutions and Innovation
- Providing methodological and scientific direction for horizon scanning and evidence products
- Managing the Stage Gate Innovation process to develop evidence products and research services
I am passionate about using scientific evidence to improve health outcomes and healthcare delivery. I have more than fifteen years experience in health technology assessment, health outcomes research, and preclinical laboratory research encompassing the areas of virology, gene therapy, and cancer medicine. I am well-versed in a wide range of health technologies including drugs, medical devices, surgical procedures, medical tests (including genetic testing).
Specialties: Health Technology Assessment, Comparative Effectiveness Reviews, study design, critical appraisal methodology (GRADE), health outcomes research, molecular medicine, product Innovation, team and program management
Health Technology Assessment
Electron microscopic in situ localization studies of Barley Yellow Dwarf Virus protein and RNA
Chinese language and culture
Team and project management
Systematic literature search
Rating the quality of individual studies
Grading the quality of the body of evidence
Comparative genomics, phylogenetics, next generation sequencing, metagenomics
Gene therapy, targeted drugs, genetic test evaluation, pathway analysis
Microsoft Office Suite: Word, Powerpoint, Excel
Webconferencing software: GoToMeeting
Reference management software: EndNote, Reference Manager
Adobe family including Acrobat and Photoshop
Decision analysis software: TreeAge
Microbiology including all aspects of maintenance and propagation of bacteria, fungi and viruses
Cell culture including all aspects of cell culture maintenance
Protein biochemistry including all common types of protein purification/immunological assays including enzyme-linked immunoadsorbent assay, gel electrophoresis, radioimmunoassay
Light microscopy including fluorescent methods and potentiometric dyes
Electron microscopy including in situ hybridisation and immunoproteinlocalization
Gene therapy including DNA cloning and sequencing, plasmid and virus purification and construction
Concepts and tools to understand, analyze, and interpret data from next generation sequencing experiments.
Module 1: Introduction to Genomic Technologies (completed with distinction)
Module 2: Genomic Data Science with Galaxy (completed)
Module 3: Python for Genomic Data Science (completed with distinction)
Assembling and leading a data science enterprise.
Module 1: A Crash Course in Data Science
Module 2: Building a Data Science Team
Module 3: Managing Data Analysis
Module 4: Data Science in Real Life
Topics covered in this course: comparative genomics, multiple sequence alignments, phylogenetics, selection analysis, next generation sequencing, metagenomics.
Theory and methods in public management and public policy
The course included modules on methods for cultural sensitivity training, moderating diverse groups, and cross-cultural project management and consulting.
The course included modules on project management methods, managing diversity, earned value management, influence without authority, and conflict resolution.
The course included modules on ethics, global regulatory strategy, pharmaceutical definition & lifecycle, regulation of pharmaceuticals and combined products, project management, effecitve communication & negotiation, and medical writing.
Social Network Analysis - University of Michigan via Coursera
Introduction to Pharmacoeconomics - ISPOR Distance Learning Program
Mendgen K., Nass P.H. (1988). The activity of powdery-mildew haustoria after feeding the host cells with different sugars, as measured with a potentiometric cyanine dye. Planta 174(2), 283-288.
Mauler-Machnik A., Nass P. (1990). Einfache Methode zur Frühdiagnose von Pseudocercosporella herpotrichoides mit dem Bayer Getreide-Diagnose-System nach Verreet/Hoffmann. Gesunde Pflanze 42, 130-132.
Nass, P.H., Jakstys B.P., D'Arcy C.J. (1995). In situ localization of barley yellow dwarf virus in oats. Phytopathology 85, 556-560.
Nass, P. H., Domier, L. L., Jakstys, B. P., and D'Arcy, C. J. (1998). In Situ Localization of Barley Yellow Dwarf Virus-PAV 17-kDa Protein and Nucleic Acids in Oats. Phytopathology 88(10), 1031-1039.
Nass, P. H., Elkins, K. L., and Weir, J. P. (1998). Antibody response and protective capacity of plasmid vaccines expressing three different herpes simplex virus glycoproteins. J Infect Dis 178(3), 611-7.
Tchorzewski, M. T., Duncan, M. D., Nass, P., Qureshi, F. G., Gearhart, P. J., Winchurch, R., and Harmon, J. W. (1998). Characterization of an aFGF gene expression vector with therapeutic potential. J Surg Res 77(2), 99-103.
Byrnes, C. K., Khan, F. H., Nass, P. H., Hatoum, C., Duncan, M. D., and Harmon, J. W. (2001). Success and limitations of a naked plasmid transfection protocol for keratinocyte growth factor-1 to enhance cutaneous wound healing. Wound Repair Regen 9(5), 341-6.
Nass, P. H., Elkins, K. L., and Weir, J. P. (2001). Protective immunity against herpes simplex virus generated by DNA vaccination compared to natural infection. Vaccine 19(11-12), 1538-46.
Tihan, T., Harmon, J. W., Wan, X., Younes, Z., Nass, P., Duncan, K. L., and Duncan, M. D. (2001). Evidence of androgen receptor expression in squamous and adenocarcinoma of the esophagus. Anticancer Res 21(4B), 3107-14.
Wan, X., Duncan, M. D., Nass, P., and Harmon, J. W. (2001). Synthetic retinoid CD437 induces apoptosis of esophageal squamous HET-1A cells through the caspase-3-dependent pathway. Anticancer Res 21(4A), 2657-63.
Wan, X., Nass, P., Duncan, M. D., and Harmon, J. W. (2001). Acidic fibroblast growth factor overexpression partially protects 3T3 fibroblasts from apoptosis induced by synthetic retinoid CD437. J Mol Med 79(2-3), 143-8.
Byrnes, C. K., Nass, P. H., Duncan, M. D., and Harmon, J. W. (2002). A nuclear targeting peptide, M9, improves transfection efficiency in fibroblasts. J Surg Res 108(1), 85-90.
Byrnes, C. K., Nass, P. H., Shim, J., Duncan, M. D., Lacy, B., and Harmon, J. W. (2002). Novel nuclear shuttle peptide to increase transfection efficiency in esophageal mucosal cells. J Gastrointest Surg 6(1), 37-42.
Byrnes, C. K., Bahadursingh, A., Akhter, N., Parinandi, N. L., Natarajan, V., Montgomery, E., Tihan, T., Duncan, M. D., Nass, P. H., and Harmon, J. W. (2003). Duodenal reflux produces hyperproliferative epithelial esophagitis-a possible precursor to esophageal adenocarcinoma in the rat. J Gastrointest Surg 7(2), 172-80.
Byrnes, C. K., Malone, R. W., Akhter, N., Nass, P. H., Wetterwald, A., Cecchini, M. G., Duncan, M. D., and Harmon, J. W. (2004). Electroporation enhances transfection efficiency in murine cutaneous wounds. Wound Repair Regen 12(4), 397-403.
Levine S., Nass P., Rogstad T. Effectiveness Guidance Document. Devices for Local Treatment of Chronic Wounds. Baltimore, MD: Center for Medical Technology Policy; 2009.
Nass P., Levine S., Yancy C. (2012). Methods for involving patients in topic generation for patient-centered comparative effectiveness research - an international perspective. Patient-Centered Outcomes Research Institute (PCORI). Available at: http://www.pcori.org/what-we-do/methodology/
Nass P. (2012). Photovoice: The Use of Photography in Participatory Healthcare Research and Integrated Care. Gaceta Sanitaria. 26:275.
Hayes Inc. Webinar Series
Basic Concepts in Nanomedicine (May 28, 2009; September 28, 2009)
Jacksonville Business Journal (Issue 25.-31. August, 2006)