Projects Handled (2003 - 2011):

  • Encapsulation of Potentially Immunotherapeutic /Immunoprophylactic peptides in novel biocompatible. nanosized Carriers for targeted delivery in IDDM- Funded by DBT. Collaborators: Dr. Rajni Rani-NII, Dr. H.B. Bohidar-JNU, Dr AK Verma-DU, Dr. GoswamiAIIMS. 
  • Design of Novel polymer based non-viral vector for gene delivery. AK Verma, DU. Funded by UGC. 
  • Detection of Polymeric nano-particulate drug delivery system for anti-cance drug by Quantitative Fluorescence Microscopy. Funded by DBT. 
  • Role of CD2 Antigen in T-cell signal Transduction pathway in Visceral Leishmaniasis (at RMRI of Medical science, ICMR).
  • Chloroquine Minimum Effective Dose (MED) evaluation on P. berghei mice model (at CDRI).


Papers submitted for publication: 

  • A. Chanchal, Anita K. Verma, Rajni Rani and H. B. Bohidar.Gelatin micro and nanoparticles prepared by phase separation and phase transition pathways. Int. Journal of Nanotechnology. (Accepted).
  • Dissolution kinetics of Intramolecular aggregates & Self folded gelatin coacervates entrapping Cycloheximide (CHX), at various pH values. A. Chanchal, H.B.Bohidar , Anita K. Verma (Journal of Nanomaterials).



  • Nano-therapeutics: in-vivo biodistribution of 99mTc Labelled- Surface coated Paclitaxel Loaded hydrophilic Biopolymeric Nanoparticles for the treatment of Hepatic cancer. Anita K. Verma & A. Chanchal International Conference on Radiation Biology & Translational Research in Radiation Biology, 2008, 10-12 Nov, Jaipur, India.
  • Nanomedicine in cancer therapeutics : Pharmacokinetics & in-vivo biodistribution of hydrophillic Drug Loaded Biopolymeric Nanoparticles vs Nano-conjugates. Anita K. Verma A. Chanchal. International Conference on Biomedical Engineering & Nanotechnology ICBENT-2008), October 21-23, 2008, Kohlapure, India.
  • Paclitaxel loaded Stimuli-Responsive biopolymeric Nanogel-particles: Preparation, Drug-Release Behaviors, in-vitro Cellular Interaction and biodistribution in tumor bearing mice model. Anita K. Verma, A. Chanchal, Ajay Kumar & H.B.Bohidar. Indo-Australian Conference on Medical Biotechnology 2008,11-12 Feb, 2008, National Institute of Immunology, New Delhi, India.
  • Polymer Therapeutics: Surface coated gelatin nanospheres for treatment of hepatic Cancer. Anita K. Verma, A. Chanchal, Ajay Vashisht & H.B. Bohidar. 5TH Annual Conference of “BIOTECHNOLOGY SOCIETY OF INDIA”"Biotech 2007" Nov 2007, Lucknow.
  • Long Circulating Drug Polymer nano-conjugates of Cisplatin – Pharmacokinetics, Release kinetics and Cellular uptake. Anita K. Verma, A. Chanchal, K. Sachin & H.B. Bohidar. Oral Presentation ESF-EMBO Symposium:Probing Interactions Between Nanoparticles/Biomaterials and Biological Systems: Alternative Approaches to Bio- and Nano-toxicity. Spain Nov. 2007.
  • Dissolution kinetics of Intramolecular aggregates & Self folded gelatin coacervates entrapping Cycloheximide (CHX), at various pH values. A. Chanchal, H.B.Bohidar , Anita K.Verma, Oral presentation at International Conference of Nanotechnology, ICNT’06, San Francisco, USA- 30th Oct-Nov2, 2006.
  • Release kinetics and cellular uptake of hydrophilic drug polymer nano-conjugate to enhance blood circulating levels of Cisplatin. Anita K. Verma, K. Sachin,A. chanchal, H. B. Bohidar. Oral presentation at Internantional Nanobioscience Conference, Aug,6-8, Pune2006.



List of Publications:

  • Anita K. Verma, A. Chanchal, R. P. Pandey, R. Vohra,N. Islam & A. K. Misra Pharmacokinetics and Biodistribution of Paclitaxel–Gelatin Nanoparticles. Int. J. Green Nanotechnology, Vol 4, Issue 4, 2012.
  • Abhishek Chanchal, S.A. Husain, A.K. Verma. In-vitro Physico-chemical evaluation of Biopolymeric Nanoparticles Journal of Pharmacy Research 2012,5(8),4042-4044.
  • A. K.Verma, R. P. Pandey, A. Chanchal, I. Siddiqui & P. Sharma (2011) - Encapsulation of Antigenic Secretory Proteins of Mycobacterium tuberculosis in Biopolymeric Nanoparticles for Possible Aerosol Delivery System, Journal of Bionanoscience, Vol. 5, 1–7, 2011. 

American Scientific Publishers. 

  • P. Kumar, R. Meena, R. Paulraj, A. Chanchal, A. K. Verma & H. B. Bohidar (2012) Fluorescence behavior of non-functionalized carbon nanoparticles and their in vitro applications in imaging and cytotoxic analysis of cancer cells. Colloids and Surface B: Biointerface, 2012, 91, 34-40. 
  • Anita Kamra Verma, Abhishek Chanchal and Ajay Kumar (2011) Potential of Negatively charged Pectin nanoparticles encapsulating Paclitaxel; Preparation & Characterization IEEE explore.
  • D Shailendran, N Pawar, A Chanchal, H.B Bohidar & Anita K Verma. (2011) Characterization and Antimicrobial activity of Nanocurcumin and Curcumin IEEE explore.
  • Anita Kamra Verma, Najmul Islam, Abhishek Chanchal and R.P.Pandey. (2011) Biopolymeric vectors for enhancing Gene delivery-A Comparative evaluation IEEE explore.
  • Anita K. Verma, R. P. Pandey, A. Chanchal, and P. Sharma (2011). Immuno-Potentiating Role of Encapsulated Proteins of Infectious Diseases in Biopolymeric Nanoparticles as a Potential Delivery System - J. Biomed. Nanotechnol. 7, 63-64.
  • Anita K. Verma, A. Chanchal & K.Chuttani (2011) Augmentation of anti-tumour activity of Cisplatin by Pectin nano-conjugates in B-16 mouse model - Pharmacokinetic s & in-vivo biodistribution of radio-labeled, hydrophillic Nano-conjugates. 2012 Int. J. Nanotechnology.
  • Anita Kamra Verma, A Chanchal & A Maitra (2010) Co-polymeric hydrophilic nanospheres for drug delivery: Release kinetics, and cellular uptake. IJEB 48, No.10, 1043-1052.






Nanoparticles Characterization

Drug Delivery


Work History

Work History
2012 - Present

Sr. Scientist (R&D)

Destiny Nanotech Pharma Pvt Ltd (DNPL)
  • Formulation & Physico-Chemical Characterization of Multilayer-Multidrug.
  • Bio-Polyemeric Nanoparticles for Targeted Drug Delivery.
  • NANO -Medicine / -Biotechnology.
2005 - 2012

Senior Research Scholar

Kirori Mal College - University of Delhi
  • Physicochemical Characterization of Given Polymer (Biopolymer).
  • Study of Drug Compatibility with given polymer.
  • Formulation of Nanoparticles from polymer & Characterization.
    1. Size Measurement by Dynamic Light Scattering (DLS), TEM & AFM.
    2. Surface Charge Measurement by Electrophoretic DLS.
    3. Surface characterization by Porometer, Viscometer, FTIR, NMR, XRD etc.
  • Physical & Chemical Drug Entrapment in Nanoparticles.
  • Drug Release Kinetic Study using Membrane Dialysis & various Mathematical Model.
  • In-vitro (cell culture) & In-vivo (animal) Cytotoxicity Study (MTT, Haemolysis, Comet Assay, Apoptotic Assay by Flow-Cytometry and Microscopy).
  • Drug loaded Nanoparticles Internalisation study by Fluorescent Microscop.
  • Tagging of Nanoparticles for Targeted Delivery & analysed by Animal Imagin.
  • Animal Handling for in-vivo work: 
  1. Imaging (fluorescent-labelled & Radio-labelled using Tc99).
  2. Pharmacokinetic & Pharmacodynamic by HPLC [On Rabbit & Mice (BALB/c, Albino Swiss, Black C-57)].
  3. Tumor Model development & Tumor Regression Study.
  4. Synergestic Effect of Nanoparticles & Drug on protein & gene expression by Western Blot and RT-PCR.
  5. Immunomodulation Study of Drug loaded Nanoparticles by Flow-Cytometry and ELISA.


2009 - 2011

Ph.D in BioSc. (Nanomedicine)

Jamia Millia Islamia
  • Synergestic Effect of Nanoparticles & Their Payload (Paclitaxel) on DNA damage in Cancer (breast) Therapy.