Work History

Work History
2012 - Present

Sr. Scientist (R&D)

Destiny Nanotech Pharma Pvt Ltd (DNPL)
  • Formulation & Physico-Chemical Characterization of Multilayer-Multidrug.
  • Bio-Polyemeric Nanoparticles for Targeted Drug Delivery.
  • NANO -Medicine / -Biotechnology.
2005 - 2012

Senior Research Scholar

Kirori Mal College - University of Delhi
  • Physicochemical Characterization of Given Polymer (Biopolymer).
  • Study of Drug Compatibility with given polymer.
  • Formulation of Nanoparticles from polymer & Characterization.
2004 - 2005

Sr. Research Fellow

LRS TB Research Institute

  • Clinical Research in Mw. Vaccine for TB patient(s) funded by DBT and Cadila Pharma jointly.

Skills

Skills

Instrumentation

  Dynamic Light Scattering (DLS) Electrophoretic DLS Viscometer, FTIR, XRD Animal Imager (fluorescent & radio labelled) Flow-Cytometry HPLC UV-Vis Spectrophotometer Fluorescent Microscopy Wester Blot & PCR

Biotechnology

Medicine

Multilayer-Multidrug

Nanoparticles Characterization

Drug Delivery

Nanoparticles

Nanoparticulate Drug Delivery

  Physicochemical Characterization of Given Polymer (Biopolymer) Study of Drug Compatibility with given polymer Formulation of Nanoparticles & Coacervate from polymer & Characterization Size Measurement by Dynamic Light Scattering (DLS), TEM & AFM Surface Charge Measurement by Electrophoretic DLS Surface characterization by Porometer, Viscometer, FTIR, NMR, XRD etc Physical & Chemical Drug Entrapment in Nanoparticles & Coacervate Drug Release Kinetic Study using Membrane Dialysis & various Mathematical Model In-vitro (cell culture) & In-vivo (animal) Cytotoxicity Study (MTT, Haemolysis, Comet Assay, Apoptotic Assay byFlow-Cytometry and Microscopy) Drug loaded Nanoparticles Internalisation study by Fluorescent Microscopy Tagging of Nanoparticles for Targeted Delivery & analysed by Animal Imaging Animal Handling for in-vivo work: Imaging (fluorescent-labelled & Radio-labelled using Tc99) Pharmacokinetic & Pharmacodynamic by HPLC [On Rabbit & Mice (BALB/c, Albino Swiss, Black C-57)] Tumor Model development & Tumor Regression Study Synergestic Effect of Nanoparticles & Drug on protein & gene expression by Western Blot and RT-PCR Immunomodulation Study of Drug loaded Nanoparticles by Flow-Cytometry and ELISA    

Education

Education
2008 - 2012

PhD

Jamia Millia Islami (Central University)
  • Synergestic Effect of Nanoparticles & Their Payload (Paclitaxel) on DNA damage in Cancer (breast) Therapy.

Guide:- Prof. Sayed Akhtar Husain, Head, Dept. of Biotechnology, JMI, Delhi.

Summary

  • Senior Research Scholar in Kirori Mal College - University of Delhi (2005 - 2012).
  • � 2 Years as Teaching Assistantship in Bioscience - Jamia Millia Islamia, Delhi (2009 - 2011).
  • � 2 years of teaching as Guest Lecture, K.M. College - Delhi University (2007 - 2009).
  •  11 months as SRF in LRS TB Research Institute - Delhi (2004 - 2005).
  •  2 years as Research Scholoar in RMRI of Medical Science - Patna (2002 - 2004).
  • � 6 months of Teaching in Zakir Husain Institute - Patna (2003).
  • � 4 months as Trainee at Central Drug Research Institute - Lucknow (2002).

CITATION link:- http://scholar.google.co.in/citations?hl=en&user=1NriAkQAAAAJ

  1. Nanotechnology Formulated Drug / Gene Delivery System Studied 

  • UV-degraded Gelatin Nanoparticles & Paclitaxel drug – (in-vitro & in-vivo study)
  • Pectin-Cisplatin Nanoconjugate – (in-vitro & in-vivo study)
  • Gelatin Nanoparticles & Doxorubicin drug – in-vitro study
  • Chitosan Nanoparticle & M.tb. CFP for Aerosol Delivery – in-vitro study
  • Carbon Nanotube & Nano-curcumin – in- vitro study
  • Delivery of GFP gene using (+)vely charged Gelatin-PEG nanoparticles
  1. Dr. Abhishek Publication with Impact Factor:-

  • Int. J. Green Nanotechnology, Vol 4, Issue 4, 2012. Impact Factor – Not available
  • Journal of Pharmacy Research 2012,5(8),4042-4044 Impact Factor – 2.50
  • Journal of Bionanoscience, Vol. 5, 1–7, 2011 Impact Factor - Not available
  • Colloids and Surface B: Biointerface, 2012, 91, 34-40 Impact Factor – 3.50
  • ieee xplore® digital library (2011) impact factor – 6.91 x 3 paper
  • J. Biomed. Nanotechnol. 7, 63-64. Inpact Factor - 4.37
  • Int. J. Nanotechnology 9; 10-12; Impact Factor – 1.33
  • Int. J. Exp Bio. 48, No.10, 1043-1052. Impact Factor – 1.19

Custom

Projects Handled (2003 - 2011):

  • Encapsulation of Potentially Immunotherapeutic /Immunoprophylactic peptides in novel biocompatible. nanosized Carriers for targeted delivery in IDDM- Funded by DBT. Collaborators: Dr. Rajni Rani-NII, Dr. H.B. Bohidar-JNU, Dr AK Verma-DU, Dr. GoswamiAIIMS. 
  • Design of Novel polymer based non-viral vector for gene delivery. AK Verma, DU. Funded by UGC. 
  • Detection of Polymeric nano-particulate drug delivery system for anti-cance drug by Quantitative Fluorescence Microscopy. Funded by DBT. 
  • Role of CD2 Antigen in T-cell signal Transduction pathway in Visceral Leishmaniasis (at RMRI of Medical science, ICMR).
  • Chloroquine Minimum Effective Dose (MED) evaluation on P. berghei mice model (at CDRI).

Custom

Symposia/Seminars/Conferences:

  • Nano-therapeutics: in-vivo biodistribution of 99mTc Labelled- Surface coated Paclitaxel Loaded hydrophilic Biopolymeric Nanoparticles for the treatment of Hepatic cancer. Anita K. Verma & A. Chanchal International Conference on Radiation Biology & Translational Research in Radiation Biology, 2008, 10-12 Nov, Jaipur, India.
  • Nanomedicine in cancer therapeutics : Pharmacokinetics & in-vivo biodistribution of hydrophillic Drug Loaded Biopolymeric Nanoparticles vs Nano-conjugates. Anita K. Verma A. Chanchal. International Conference on Biomedical Engineering & Nanotechnology ICBENT-2008), October 21-23, 2008, Kohlapure, India.
  • Paclitaxel loaded Stimuli-Responsive biopolymeric Nanogel-particles: Preparation, Drug-Release Behaviors, in-vitro Cellular Interaction and biodistribution in tumor bearing mice model. Anita K. Verma, A. Chanchal, Ajay Kumar & H.B.Bohidar. Indo-Australian Conference on Medical Biotechnology 2008,11-12 Feb, 2008, National Institute of Immunology, New Delhi, India.
  • Polymer Therapeutics: Surface coated gelatin nanospheres for treatment of hepatic Cancer. Anita K. Verma, A. Chanchal, Ajay Vashisht & H.B. Bohidar. 5TH Annual Conference of “BIOTECHNOLOGY SOCIETY OF INDIA”"Biotech 2007" Nov 2007, Lucknow.
  • Long Circulating Drug Polymer nano-conjugates of Cisplatin – Pharmacokinetics, Release kinetics and Cellular uptake. Anita K. Verma, A. Chanchal, K. Sachin & H.B. Bohidar. Oral Presentation ESF-EMBO Symposium:Probing Interactions Between Nanoparticles/Biomaterials and Biological Systems: Alternative Approaches to Bio- and Nano-toxicity. Spain Nov. 2007.
  • Dissolution kinetics of Intramolecular aggregates & Self folded gelatin coacervates entrapping Cycloheximide (CHX), at various pH values. A. Chanchal, H.B.Bohidar , Anita K.Verma, Oral presentation at International Conference of Nanotechnology, ICNT’06, San Francisco, USA- 30th Oct-Nov2, 2006.
  • Release kinetics and cellular uptake of hydrophilic drug polymer nano-conjugate to enhance blood circulating levels of Cisplatin. Anita K. Verma, K. Sachin,A. chanchal, H. B. Bohidar. Oral presentation at Internantional Nanobioscience Conference, Aug,6-8, Pune2006.

Custom

Certifications

Certifications

Professional Training

NIPER and AIIMS

Papers Submitted for Publication

Academical Research

American Scientific Publishers

Academical Research

List of Publications

Academical Research