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Chetan Nimgulkar

Scientific Manager at GVK Biosciences

Work experience

Nov 2015Present

Scientific Manager 

GVK Bio-sciences, Hyderabad
  • Re-purposing of various NCEs molecules for prevention and treatment of Pulmonary Arterial Hypertension (PAH), NASH, IPF, and tumor xenograft using in vivo model
  • PK-PD correlation and safety evaluation of new chemical entities
  • Study design, experiment execution and report writing
  • Study report submitted to Investigation New Drug (IND) application: 01
Nov 2014Nov 2015

Post Doctoral Fellow

GVK Biosciences
  • Establishment of in vivo animal model for Pulmonary Arterial Hypertension (PAH) and tumor xenograft
  • PK-PD correlation and safety evaluation of new chemical entities
Feb 2009Feb 2014

Junior and Senior Research Fellow

National Institute of Nutrition, (ICMR), Dept of Health Research, Min. of H &FW, Govt of India, Hyderabad
  • Formulation of hypothesis, objectives to assess the proof of concept / mechanism
  • Pharmacological efficacy and safety evaluation of drugs using in vitro and in vivo techniques
  • Conducted toxicological studies (OECD 420, 423 and 425) for various compounds


Feb 2009Feb 2015

PhD - Pharmacology

Osmania University, Hyderabad

The in vitro and in vivo studies established the proof of mechanism, that the armoury of polyphenols in combination, potentially abrogates CD36 signalling mediated pathogenic foam cell formation and promote their  emigration from the intima resulted in atheroinflammatory lesion regression.

Jun 2006Jul 2008

M. Pharm - Pharmacology

North Maharashtra University, Jalgaon

Pharmacological mechanistic anti-asthmatic and antianaphylactic activities of a homeopathic drug - B. orientalis were established for the first time. The thermoreversible (PF-127) nasal gel of B. orientalis were formulated which showed better anti-asthmatic activity.

Jun 2002Jun 2006

B. Pharm

Pune University, Pune



  • Outstanding Achiever for exceptional performance by GVK Biosciences- 02/2017
  • Selected Junior (02/2009 - 02/2011) and Senior Research Fellow (02/2011 -02/2014) Awarded - National Institute of Nutrition, Indian Council of Medical Research, Govt. of India.
  • Young Pharmacologist Govind Achari Prize by Indian Pharmacological Society - 2011
  • First prize - State level Inter-Pharmacy scientific presentation, Pune, Maharashtra,  India - 2005
  • Best outgoing student of the year - College of Pharmacy, Pune, Maharashtra, India - 2005


  • Nimgulkar C, Ghosh S, Shankar Anand B, Uday Kumar P, Surekha M V, Madhusudhanachary  P, Annapurna B R, Dinesh Kumar B. Combination of spices and herbal extract restores macrophage foam cell migration and abrogates the athero-inflammatory signalling cascade of atherogenesis,  Vascul Pharmacol, 2015; 72: 53-63. [PMID: 25869517]
  • Nimgulkar C, Edula S, Racha V, Chalamaiah M, Shyam P, Ravindranath A,  Dinesh Kumar B., Role of in silico COX2 molecular docking bioinformatics tool and in vivo carrageenan induced various inflammatory phase in mouse and rat models, in evaluation of anti-inflammatory activity of molecules. Int J Pharma Res & Rev, 2014; 3(4):57-65
  • M. Chalamaiah, R. Hemalatha, T. Jyothirmayi, Prakash V. Diwan, P. Uday kumar, Chetan Nimgulkar, B. Dinesh kumar., Immunomodulatory effects of protein hydrolysates from Rohu (Labeo rohita) egg (roe) in BALB/c mice, Food Res Int, 2014, 62, 1054–1061 [doi:10.1016/j.foodres.2014.05.050]
  • Panpatil VV, Tattari S, Kota N, Nimgulkar CC, Polasa K. In-vitro evaluation on antioxidant  and anti-microbial activity of spice extracts of ginger, turmeric and garlic. J Pharmacognosy and Phytoch; 2013; 2 (3): 143-148
  • Sunitha K, Bhaskara Chary K, Nimgulkar CC, Dinesh Kumar B, Manohar Rao D., Identification, quantification and antioxidant activity of Secondary metabolites in leaf and callus extracts of Coleus forskohlii. Int J Pharma Bio Sci; 2013; 4(3): (B) 1139 – 1149.
  • Nimgulkar CC, Patil SD, Dinesh Kumar B. Anti-asthmatic and anti-anaphylactic activity of Blatta orientalis mother tincture. Homeopathy; 2011; 100: 138-43 [PMID: 21784330]
  • Nimgulkar CC, Joshi AA. Anti-Asthmatic and Anti-Anaphylactic Activity of Helicanthus  elastica Desr. Pharmacologyonline; 2010; 2: 14-31
  • Nimgulkar CC, Patil SD, Chauk DS. Evaluation of Blatta orientalis (Φ) nasal gel formulation in milk aspiration induced eosinophilia. Pharm Dev Technol; 2009; 14(4): 435–441 [PMID: 19552565]
  • Nimgulkar CC, Patil SD. Role of simulator in surgical blood pressure. AATEX 14, Special Issue; 2008; 14: 221-223


  • Arteriosclerosis, Thrombosis and Vascular Biology (AHA-ATVB)- 2013 (A501) title “Poly Herbal Formulation Prevents Foam Cell Formation Possibly Through Attenuation of CD36 Scavenger Receptor Signalling Cascade”, at FL, USA - (ePoster presentation - 1st - 3rd May 2013)
  • 6th World congress on Alternatives and Animal use in the life sciences, title "Role of simulator in surgical blood pressure" Tokyo,  JAPAN  - (Oral presentation - 21st -25th August 2007)
  • 42nd Nutrition Society of India National meeting, Mumbai Chapter, Mumbai : Nimgulkar CC, Polasa K, Venkaiah K, Dinesh Kumar B. Combination ofNutraceutical (Garlic, Ginger, Turmeric) and Herbal (Terminalia arjuna, Cyprus rotundus) as Potential Anti-oxidant and Anti-inflammatory agents - (Oral Presentation - 09/2010)
  • 29th Annual conference of Society of Toxicology, India at NIN (ICMR), Hyderabad, ‘Safety efficacy validation of traditional medicinal plant Sarcostemma  acidum’  -(Poster - 2009)
  • 58th Indian Pharmaceutical Congress at Mumbai, ‘Spectrometric determination of Meloxicam from solid and gel dosage forms - (Poster - 2007)
  • APTI at Visakhapatnam: ‘Drug receptor binding’ - (Poster - 2004) 
  • First Indian congress on Alternatives to the use of animals in research, testing and education, Chennai, India - (Demonstration - 29th -31st January 2007)


  • Life member of Indian Pharmacological Society (IPS)
  • Life member of Nutrition Society of India (NSI)
  • American Heart Association (AHA-ATVB)


Dr. Muthusamy Shanmuganathan, PhD

2nd Clinical Scientific Expert


Hyderabad, India.
M: +91-7207136808
Email: [email protected]

Dr. J. B. Gupta, Chief Scientific Officer
Collaborative Research
GVK Biosciences Private Limited, Hyderabad: 500 076, India
M: +91-0986656310
Email ID: [email protected]

Dr. B. Dinesh Kumar, PhD, FAPASc, FIPS

Scientist ‘F’ (Deputi Director - Sr.) and PCT-Coordinator
Center for Advanced Research for Preclinical Toxicology Center
Food and Drug Toxicology Research Center
National Institute of Nutrition (ICMR), Govt. of India, Hyderabad, 500 007, India.
T: +91 (040) 27197322, M: +91 9849082088
Email: [email protected]