Dr. Rakesh Asthana

Dr. Rakesh Asthana

Work History

Work History

CENTRAL DRUG RESEARCH INSTITUTE, LUCKNOW IND

Education

Education

M.Sc, Ph.D (CHEMISTRY),

DR. B. R .AMBEDKAR UNIVERSITY, AGRA, U.P. INDIA

Ph.D (CHEMISTRY)

DR. B. R .AMBEDKAR UNIVERSITY, AGRA, U.P. INDIA

Interest

Research,Games, Cricket, Making good fraiends,

Summary

Experience:    32 years inR & D

Publications: Research Papers -Six

                     Products Developed-Three

                      Patent Taken        -One

                      Process Developed -Five

Supervision:   

Res. work:    M. Pharma./ M.Sc Pharmaceutical Chemistry (Thesis/ Project-  12 NOS.)            

Major achievements:

Process Dev.Drug /Int.            Name

,,Int.        6-methoxytetralone-1

,,                       ,,16-DPA

      ,,                       ,,DHA

      ,,                       ,,N-Bromoacetamide

      ,,                       ,,LTA

Products DrugNorethisterone

     ,,    ,,Isolation of Gossypol acetate -A MALE       

                                                    ANTIFERTILITY  DRUG from NP

                        ,,                          Isolated and process developed for the

                                                    CDRI antidiabetic drug CT-1 from plant

                                                    "SWERTIA CHIRAYITA".

List of Publications:

1.Assessment of systemic interaction between Swertia chirata extract

    and its Bioactive constituents in rabbits. Satyendra Suryawanshi,

    R. K. Asthana, R. C. GuptaPhytotherapy Research. 2009, 23,

1036-1038

2.Simultaneous estimation of Mangiferin & four secoiridoid glycosides

    in rat plasma using liquid chromatography tandem mass spectrometry

    & its application to pharma-cokinetic study of herbal preparatiom.

    Satyendra Suryavanshi, R. K. Asthana & Ram

C Gupta.J .Chromatography.B. 2007.858(1-2), 211-219

3.  Liquid chromatography/tandem mass spectrometric study and analysis

    of xanthoneandsecoiridoid glycoside composition of Swertia chirata, a

     potent antidiabetic. Suryawanshi Satyendra, Mehrotra Nitin, Asthana

     R.K & Gupta Ram C. RapidCommunication in Mass spectrometry

    2006, 20(24), 3761

 4.Swertia chirayita mediated modulation of Interleukin 1-β, Interleukin-6,

      Interleukin-10, Interleukin-γ and tumer Necrosis factor-α in arthritic mice. 

      Sirish K, I.V.M.L.R,Paul, B.N, Asthana R, Saxena A, Mehrotra S, Rajan   

      G. Immunopharmacology andImmunotoxicology. 2003, 4, 573-583

5.    A xanthones from Swertia chirayita. Asthana, R.K., Sharma, N. K., 

      Kulshreshtha, D.K., Chatterjee, S. K.. Phytochemistry. 1991, 30,1037

6.Hypoglycaemic effect of Swerchirin from hexane fraction of Swertia

      chirayita.Bajpai, M.B., Asthana, R. K., Sharma, N. K, Chatterjee, S.   

K.,  Mukherjee, S. K.Planta Med.1991,57,102

 Patent Taken:

    Bajpai, Madhu. Bala., Chandrasekhar, Bysani., Mukherjee,

    Bhaswar., Mathur,Swaroop Kumar., Asthana, Rakesh Kumar.,

    Palvi, Sudhir, Kumar., Chakravarty,Ramendra, Bhushan.,

    Sengupta, Ashok, Kumar., Banerjee, Ranjan., Sharma,

Narendra. Kumar., Mehrotra, Bishan. Narain., Kulshreshtha, 

Dinesh. Kumar.,  Nigam, Shyam. Kishore., Chatterjee, Sunil. Krishna.,   

    Mukherjee, Surat. Kumar. (Council ofScientific and Industrial Research, 

    India). An improved process for the isolation of hypoglycemic Swerchirin

    from Swertia chirayita. Indian IN 179, 769 (Cl. A61

K31/100), 29 Nov 1997; Appl. 1990/ 0E 886, 5 Sept. 1990;9 pp. (Eng

Objective

TO SHARE OUR EXPERIENCE WITH YOUNG "NATURAL PRODUCT RESEARCHERS". HELP THEM IN THEIR RESEARCH.