Ananthakrishnan Sankaranarayanan

Ananthakrishnan Sankaranarayanan

Work History

Work History
Aug 2008 - Present

Assistant Professor- Medicinal & Organic Chemistry

University of New Orleans


  • Independently established a fully equipped Medicinal Chemistry and Electrophysiology Laboratory
  • Design of potent and selective small molecule Kv1.5 blocker for treating AF – Funded by Louisiana Board of Regents –Research Competitiveness Subprogram (2009-2012) ($150,000)
  • Design of heterocyclic scaffolds for developing toxin-mimetics as novel pharmacological tools – Funded by UNO summer research program (June 2010 – August 2010) ($15000)
Sep 2003 - Jul 2008

Postdoctoral Research Associate-Pharmacology

University of California, School of Medicine


  • Design, synthesis and development of PAP-1, a novel potent and selective small molecule Kv1.3 blocker as an immunosuppressant (US 20060079535, A1, April 13, 2006, EPO 05808984.8-1216-US2005035572)
  • Design, synthesis and development of SKA-31, a novel potent and selective KCa3.1 activator for treating epilepsy, stress-induced hypertension and ataxia (Molecular PharmacologyFebruary 2009 vol. 75 no. 2 281-295)
Apr 2002 - Sep 2003

Research Specialist

Texas A&M University


  • Grant Funded ($23,000) Co-PI Grapefruit Drug Interaction

  • Designed a large-scale ion exchange resin column and a medium pressure liquid chromatography system for isolation and characterization of novel anti-cancer limonoids and flavanoids from Citrus (prep. HPLC, MPLC).
Oct 2000 - Mar 2002

Sr. Scientist

John F Welsh Technology Center (GEITC)
  • Bridge assignment at Morgantown plant (WV), Dec 2000. Optimization of the overall and component mass balance for the manufacture of Ultranox-626 (organophosphite antioxidant
  • Design of new organophosphites as antioxidants
  • Design of new monomers for weatherable polymers (prevention of photo-Fries rearrangement)
Aug 1998 - Sep 2000

Sr. Executive-Group Leader

Color Chem (Clariant)

  •  Development and Optimization of diketene based intermediates for pharmaceuticals, electronic chemicals, dyes, pigments; Study of reactions at high concentration 


Medicinal Chemistry Scientist with expertise in translational research, 8 years of experience in lead design/ discovery/ optimization, in vitro and in vivo pharmacology and electrophysiology. Process Research and Development Scientist ( Green Belt Certified) with 5 years of industrial experience in organic synthesis, scale-up and commercialization of drugs, fine chemicals and intermediates for drugs, antioxidants and diketene based organic chemicals.

Process Chemistry

Postdoctoral Research Associate Mar 1998-July 1998

Imperial Chemical Industries (ICI), Thane, India

  • Synthesis of α-hydroxylmethyl acrylate monomers by Baylis Hilman reaction, design and synthesis of lactone based nonionic surfactants

Doctoral Research Assistant Aug 1994-Nov 1998

University Institute of Chemical Technology, Mumbai, India

  • Synthesis of Fine Chemicals with an Emphasis on Process Development

Officer, Research & Development-SyntheticsJul 1994-Nov 1994

Food, Drugs & Chemicals Ltd, Mumbai, India

  • Scale-up of Fluconazole (orally bio-available antifungal agent)

Masters Research AssistantAug 1992–Nov 1994

  • Synthesis and scale-up of Fluconazole (antifungal) and Flunnarizine (antihistaminic)

Executive Production, Bulk Drugs, Oct 1991-Jul 1992

Merind Ltd (Merck Sharp & Dome), Mumbai, India

  • Supervision, planning and regular production monitoring of Dexamethazone, Dexamethazone disodium phosphate (parenteral)
  • Scale-up and optimization of process parameters for the manufacture of Amytriptyline HCl, Norfloxazin, Amiloride HCl,

Trainee Production Chemist, Colgate Palmolive (India) Ltd, Mumbai, IndiaJul 1990-Jul 1991

  • Regular production of Colgate-dental cream (86.4 ton per day)

Research & Development Chemist, Dec 1989-May 1990

U.S.Vitamins (India) Ltd, Mumbai, India

  • Process Research and Development of p-Hydroxyphenylacetamide, Nitrendipine, Enalapril maleate


Dec 1994 - Jun 1998

Ph.D (Tech)

University Institute of Chemical Technology, Mumbai, India



Process design and scale up

Lab management

Lead discovery